Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | MME | P08473 | 3/20 | 0.47 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319533 | 1.00 | CTSK (0.47) | CTSKMMEECE1 | |
| SCHEMBL7319525 | 1.00 | CTSK (0.47) | CTSKMMEECE1 | |
| SCHEMBL7318546 | 1.00 | CTSK (0.47) | CTSKMMEECE1 | |
| SCHEMBL7319871 | 0.86 | CTSK (0.46) | CTSKMMEECE1 | |
| SCHEMBL7316369 | 0.86 | CTSK (0.46) | CTSKMMEECE1 | |
| SCHEMBL7314091 | 0.86 | CTSK (0.46) | CTSKMMEECE1 | |
| SCHEMBL7323956 | 0.86 | CTSK (0.46) | CTSKMMEECE1 | |
| SCHEMBL7383267 | 0.86 | CTSK (0.46) | CTSKMMEECE1 | |
| SCHEMBL7309270 | 0.84 | CTSL (0.46) | MMEECE1 | |
| SCHEMBL7329474 | 0.84 | CTSL (0.46) | MMEECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527761-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | Beecham Group p.l.c. (GB) | 1993-02-24 | — | — | EP | disclosed |
| EP-0527764-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | Beecham Group p.l.c. (GB) | 1993-02-24 | — | — | EP | disclosed |
| WO-1991015507-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | BEECHAM GROUP PLC (GB) | 1991-10-17 | — | — | WO | disclosed |
| WO-1991015506-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | BEECHAM GROUP PLC (GB) | 1991-10-17 | — | — | WO | disclosed |