Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 9/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316425 | 0.93 | ALDH1A1 (0.44) | LTB4R2MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL7317198 | 0.90 | LTB4R2 (0.41) | CNR2LTB4R2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7319239 | 0.84 | NPC1 (0.41) | MEN1KMT2ANPC1ALDH1A1HTT | |
| SCHEMBL7265380 | 0.83 | CNR2 (0.43) | CNR2LTB4R2MEN1KMT2AALDH1A1 | |
| SCHEMBL7316351 | 0.81 | NPC1 (0.55) | MEN1KMT2ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL7375088 | 0.76 | TDP1 (0.40) | MEN1KMT2AALDH1A1 | |
| SCHEMBL7321024 | 0.75 | RAB9A (0.46) | KMT2ASMN1; SMN2NPC1ALDH1A1HTT | |
| SCHEMBL7267053 | 0.75 | ALDH1A1 (0.45) | LTB4R2MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL7318507 | 0.74 | NPC1 (0.40) | MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7318543 | 0.73 | SMN1; SMN2 (0.47) | MEN1KMT2ASMN1; SMN2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280956-B1 | THIAZOLIDINE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1992-10-21 | — | — | EP | claimed |
| US-4857537-A | PREVENTING AMNESIA | ONO PHARMACEUTICAL CO., LTD. (JP) | 1989-08-15 | — | — | US | claimed |
| EP-0280956-A1 | Thiazolidine derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-09-07 | — | — | EP | claimed |