Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.36 |
| ▸ | LSS | P48449 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319239 | 0.90 | NPC1 (0.41) | RAB9AHTTALDH1A1NPC1CCR1 | |
| SCHEMBL7316351 | 0.89 | NPC1 (0.55) | RAB9AALDH1A1NPC1SMN1; SMN2KMT2A | |
| SCHEMBL7318543 | 0.87 | SMN1; SMN2 (0.47) | RAB9AHTTALDH1A1NPC1CCR1 | |
| SCHEMBL10584481 | 0.86 | NPC1 (0.38) | RAB9ANPC1CCR1LSSKMT2A | |
| SCHEMBL7318507 | 0.83 | NPC1 (0.40) | RAB9ANPC1KMT2A | |
| SCHEMBL7317198 | 0.83 | LTB4R2 (0.41) | RAB9AHTTALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL7271874 | 0.81 | CCR1 (0.50) | RAB9AHTTALDH1A1CCR1SMN1; SMN2 | |
| SCHEMBL7369576 | 0.80 | CASP3 (0.36) | KMT2A | |
| SCHEMBL7317320 | 0.78 | KMT2A (0.45) | RAB9AALDH1A1NPC1SMN1; SMN2KMT2A | |
| SCHEMBL7322701 | 0.77 | METAP2 (0.40) | ALDH1A1PKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280956-B1 | THIAZOLIDINE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1992-10-21 | — | — | EP | claimed |
| US-4857537-A | PREVENTING AMNESIA | ONO PHARMACEUTICAL CO., LTD. (JP) | 1989-08-15 | — | — | US | claimed |
| EP-0280956-A1 | Thiazolidine derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-09-07 | — | — | EP | claimed |