Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CHRNA1 | P02708 | 4/20 | 0.41 |
| ▸ | CHRNG | P07510 | 4/20 | 0.41 |
| ▸ | CHRNB1 | P11230 | 4/20 | 0.41 |
| ▸ | CHRND | Q07001 | 4/20 | 0.41 |
| ▸ | ITGAV | P06756 | 2/20 | 0.41 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.41 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRB2 | P62993 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7352151 | 0.87 | ITGB3 (0.44) | ITGB3ITGA2BITGAVITGB5ITGB6 | |
| SCHEMBL8408579 | 0.84 | ITGB3 (0.46) | ITGB3ITGA2BPTPN1GRB2 | |
| SCHEMBL7343916 | 0.82 | ITGB3 (0.59) | ITGB3ITGA2BPTPN1 | |
| SCHEMBL7348381 | 0.82 | ITGB3 (0.59) | ITGB3ITGA2BPTPN1 | |
| SCHEMBL7314892 | 0.82 | ITGB3 (0.59) | ITGB3ITGA2BPTPN1 | |
| SCHEMBL7378604 | 0.82 | ITGB3 (0.59) | ITGB3ITGA2BPTPN1 | |
| SCHEMBL9505510 | 0.79 | ITGB3 (0.49) | ITGB3ITGA2B | |
| SCHEMBL10444991 | 0.79 | ITGB3 (0.48) | ITGB3ITGA2BPTPN1CHRNA1CHRNG | |
| SCHEMBL13476852 | 0.78 | MMP1 (0.52) | — | |
| SCHEMBL7321414 | 0.78 | EPHX2 (0.54) | ITGB3ITGA2BPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0494248-A4 | ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES | — | 1992-08-26 | — | — | EP | disclosed |
| EP-0494248-A1 | ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-07-15 | — | — | EP | disclosed |
| WO-1991004746-A1 | ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1991-04-18 | — | — | WO | disclosed |
| US-4952562-A | TREATMENT OF CARDIOVASCULAR DISORDERS | RORER PHARMACEUTICAL CORPORATION (US) | 1990-08-28 | — | — | US | disclosed |