Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 14/20 | 0.52 |
| ▸ | NQO2 | P16083 | 1/20 | 0.48 |
| ▸ | TNFSF11 | O14788 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
| ▸ | HTR1E | P28566 | 1/20 | 0.46 |
| ▸ | HTR1F | P30939 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | IDE | P14735 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309785 | 0.89 | NQO2 (0.48) | HTR6NQO2TNFSF11HTR1ADRD2 | |
| SCHEMBL7314748 | 0.89 | HTR6 (0.49) | HTR6NQO2HTR1ADRD2HTR1D | |
| SCHEMBL7307708 | 0.88 | HTR6 (0.47) | HTR6NQO2TNFSF11HTR1ADRD2 | |
| SCHEMBL7309156 | 0.87 | HTR6 (0.48) | HTR6NQO2HTR1ADRD2HTR1D | |
| SCHEMBL7437268 | 0.86 | HTR6 (0.71) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL7316364 | 0.86 | HTR6 (0.49) | HTR6NQO2HTR1ADRD2HTR1D | |
| SCHEMBL7310220 | 0.85 | HTR6 (0.53) | HTR6NQO2HTR1ADRD2HTR1D | |
| SCHEMBL7311385 | 0.81 | HTR6 (0.44) | HTR6NQO2HTR1ADRD2HTR1D | |
| SCHEMBL7316466 | 0.80 | HTR6 (0.41) | HTR6NQO2TNFSF11HTR1ADRD2 | |
| SCHEMBL5237100 | 0.78 | HTR6 (0.59) | HTR6NQO2HTR1ADRD2HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020004198-A1 | Novel anti-infectives | SMITHKLINE BEECHAM CORPORATION | 2002-01-10 | — | — | US | disclosed |
| US-20010007877-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION | 2001-07-12 | — | — | US | disclosed |
| WO-2001034146-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010007877-A1 | NOVEL ANTI-INFECTIVES | CTSL, MMP8, SERPINB1 | HTR6 4503/4885NQO2 1569/4885TNFSF11 3041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.