Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.61 |
| ▸ | CCR3 | P51677 | 1/20 | 0.61 |
| ▸ | DRD2 | P14416 | 2/20 | 0.57 |
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | BACE1 | P56817 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.53 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8315434 | 0.92 | ACHE (0.71) | ACHESIGMAR1CCR3DRD2DRD4 | |
| SCHEMBL4148010 | 0.89 | HRH3 (0.59) | ACHESIGMAR1CCR3DRD2DRD4 | |
| SCHEMBL6182247 | 0.89 | HRH3 (0.59) | ACHESIGMAR1CCR3DRD2DRD4 | |
| SCHEMBL5116305 | 0.89 | HRH3 (0.59) | ACHESIGMAR1CCR3DRD2DRD4 | |
| SCHEMBL13432184 | 0.84 | MC4R (0.70) | ACHESIGMAR1CCR3DRD2DRD4 | |
| SCHEMBL18477518 | 0.83 | FUCA1 (0.55) | ACHESIGMAR1CCR3DRD2DRD3 | |
| SCHEMBL3352682 | 0.82 | SIGMAR1 (0.68) | ACHESIGMAR1CCR3DRD2DRD4 | |
| SCHEMBL7234535 | 0.82 | ALDH1A1 (0.68) | SIGMAR1DRD4ALDH1A1 | |
| SCHEMBL6503563 | 0.81 | FUCA1 (0.56) | ACHESIGMAR1CCR3DRD2DRD3 | |
| SCHEMBL1232375 | 0.81 | ACHE (0.67) | ACHESIGMAR1CCR3DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4032642-A | SEDATIVES, TRANQUILIZERS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1977-06-28 | — | — | US | disclosed |
| US-3956296-A | ANTIINFLAMMATORY, SEDATIVES, TRANQUILIZERS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1976-05-11 | — | — | US | disclosed |