Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.69 |
| ▸ | DRD2 | P14416 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | HTR1A | P08908 | 1/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7310794 | 0.99 | SIGMAR1 (0.67) | SIGMAR1DRD2MEN1TP53CYP1A2 | |
| SCHEMBL10656309 | 0.87 | DRD2 (0.71) | SIGMAR1DRD2OPRM1 | |
| SCHEMBL10653140 | 0.87 | DRD2 (0.71) | SIGMAR1DRD2OPRM1 | |
| SCHEMBL10653134 | 0.87 | DRD2 (0.71) | SIGMAR1DRD2OPRM1 | |
| SCHEMBL7480157 | 0.84 | DRD2 (0.74) | DRD2SLC6A4 | |
| SCHEMBL9521523 | 0.83 | SIGMAR1 (1.00) | SIGMAR1DRD2MEN1TP53CYP1A2 | |
| SCHEMBL7402939 | 0.82 | SIGMAR1 (0.75) | SIGMAR1DRD2MEN1TP53CYP1A2 | |
| SCHEMBL21222765 | 0.82 | DRD2 (1.00) | SIGMAR1DRD2SLC6A4 | |
| SCHEMBL29914653 | 0.82 | DRD2 (1.00) | SIGMAR1DRD2SLC6A4 | |
| SCHEMBL8091036 | 0.81 | SIGMAR1 (0.76) | SIGMAR1DRD2MEN1TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364867-A | For treatment of psychosis | STERLING WINTHROP INC. (US) | 1994-11-15 | — | — | US | claimed |