Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 8/20 | 0.77 |
| ▸ | GABRA5 | P31644 | 8/20 | 0.77 |
| ▸ | GABRA3 | P34903 | 8/20 | 0.77 |
| ▸ | GABRA2 | P47869 | 7/20 | 0.77 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.77 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.77 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.77 |
| ▸ | GABRP | O00591 | 3/20 | 0.77 |
| ▸ | GABRD | O14764 | 3/20 | 0.77 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.77 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.77 |
| ▸ | GABRE | P78334 | 3/20 | 0.77 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.77 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.77 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.77 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.77 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Delorazepam SCHEMBL157332 | 0.87 | GABRA1 (1.00) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| Delorazepam SCHEMBL29375434 | 0.87 | GABRA1 (1.00) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| Delorazepam SCHEMBL32681132 | 0.87 | GABRA1 (1.00) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL3828708 | 0.86 | GABRA1 (0.70) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL7720989 | 0.85 | GABRA1 (0.77) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| Phenazepam SCHEMBL416137 | 0.85 | GABRA1 (1.00) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL11772087 | 0.85 | GABRA1 (0.77) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL2615274 | 0.85 | GABRA1 (0.73) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| 7-Aminoclonazepam SCHEMBL11453747 | 0.85 | GABRA1 (0.77) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL9378946 | 0.85 | GABRA1 (0.77) | GABRA1GABRA5GABRA3GABRA2GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9827315-B2 | Compositions of pharmaceutical actives containing diethylene glycol monoethyl ether or other alkyl derivatives | THEMIS MEDICARE LIMITED (IN) | 2017-11-28 | — | — | US | disclosed |
| US-20160082016-A1 | Use of Clonazepam in Combination with Antibiotic in the Treatment of Bacterially Induced Meningitis | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2016-03-24 | — | — | US | disclosed |
| US-20140296191-A1 | COMPOSITIONS OF PHARMACEUTICAL ACTIVES CONTAINING DIETHYLENE GLYCOL MONOETHYL ETHER OR OTHER ALKYL DERIVATIVES | THEMIS MEDICARE LIMITED (IN) | 2014-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296191-A1 | COMPOSITIONS OF PHARMACEUTICAL ACTIVES CONTAINING DIETHYLENE GLYCOL MONOETHYL ETHER OR OTHER ALKYL DERIVATIVES | DSG1, DEGS1, PLA2G2E | GABRA1 4058/4885GABRA5 3492/4885GABRA3 4137/4885 |
| US-20160082016-A1 | Use of Clonazepam in Combination with Antibiotic in the Treatment of Bacterially Induced Meningitis | GABBR1, GABBR2, GABRA4 | GABRA1 8/4885GABRA5 6/4885GABRA3 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.