Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 13/20 | 0.41 |
| ▸ | MMP13 | P45452 | 13/20 | 0.41 |
| ▸ | MMP1 | P03956 | 11/20 | 0.41 |
| ▸ | MMP2 | P08253 | 4/20 | 0.41 |
| ▸ | MMP8 | P22894 | 4/20 | 0.41 |
| ▸ | MMP12 | P39900 | 4/20 | 0.41 |
| ▸ | MMP14 | P50281 | 4/20 | 0.41 |
| ▸ | MMP16 | P51512 | 4/20 | 0.41 |
| ▸ | MMP3 | P08254 | 3/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 8/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7318787 | 0.90 | MMP13 (0.48) | MMP9MMP13MMP1MMP2MMP8 | |
| SCHEMBL7324855 | 0.83 | MMP9 (0.48) | MMP9MMP13MMP1MMP2MMP8 | |
| Hydrochloric Acid SCHEMBL7319131 | 0.82 | MMP9 (0.47) | MMP9MMP13MMP1MMP2MMP8 | |
| SCHEMBL7321745 | 0.82 | MMP13 (0.49) | MMP9MMP13MMP1MMP2MMP8 | |
| SCHEMBL7311156 | 0.81 | KDM4E (0.44) | MMP9MMP13MMP1MMP2MMP8 | |
| SCHEMBL7322262 | 0.81 | LMNA (0.43) | MMP9MMP13MMP1MMP2MMP8 | |
| SCHEMBL7310011 | 0.81 | MMP13 (0.51) | MMP9MMP13MMP1MMP2MMP8 | |
| SCHEMBL7320602 | 0.80 | MMP9 (0.47) | MMP9MMP13MMP1MMP2MMP8 | |
| SCHEMBL7322248 | 0.80 | MMP13 (0.43) | MMP9MMP13MMP1MMP2MMP8 | |
| Hydrochloric Acid SCHEMBL7323688 | 0.79 | MMP13 (0.51) | MMP9MMP13MMP1MMP2MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929097-A | INHIBIT TUMOR NECROSIS FACTOR-ALPHA CONVERTING ENZYME | AMERICAN CYANAMID COMPANY (US) | 1999-07-27 | — | — | US | disclosed |