Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 8/20 | 0.41 |
| ▸ | MMP9 | P14780 | 8/20 | 0.41 |
| ▸ | MMP1 | P03956 | 6/20 | 0.41 |
| ▸ | MMP2 | P08253 | 6/20 | 0.41 |
| ▸ | MMP12 | P39900 | 6/20 | 0.41 |
| ▸ | MMP8 | P22894 | 5/20 | 0.41 |
| ▸ | MMP14 | P50281 | 5/20 | 0.41 |
| ▸ | MMP16 | P51512 | 5/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.41 |
| ▸ | MMP3 | P08254 | 3/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311156 | 0.92 | KDM4E (0.44) | FFAR4ALDH1A1MMP13MMP9MMP1 | |
| SCHEMBL7318787 | 0.91 | MMP13 (0.48) | ALDH1A1MMP13MMP9MMP1MMP2 | |
| SCHEMBL7322737 | 0.90 | KMT2A (0.39) | ALDH1A1MMP2NAMPTMAPK8SMN1; SMN2 | |
| SCHEMBL7317521 | 0.90 | MMP13 (0.41) | LMNAMMP13MMP9MMP1MMP2 | |
| SCHEMBL7316579 | 0.90 | KDM4E (0.44) | LMNAALDH1A1MMP13MMP9MMP1 | |
| SCHEMBL7322032 | 0.90 | MMP13 (0.40) | LMNAALDH1A1MMP13MMP9MMP1 | |
| SCHEMBL7324047 | 0.89 | GABRG2 (0.42) | LMNAFFAR4MMP13MMP9MMP1 | |
| SCHEMBL7316215 | 0.89 | MMP13 (0.41) | LMNAALDH1A1MMP13MMP9MMP1 | |
| SCHEMBL7319136 | 0.88 | SMN1; SMN2 (0.40) | LMNAALDH1A1MMP13MMP9MMP1 | |
| SCHEMBL7317430 | 0.87 | MMP9 (0.44) | LMNAALDH1A1MMP13MMP9MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929097-A | INHIBIT TUMOR NECROSIS FACTOR-ALPHA CONVERTING ENZYME | AMERICAN CYANAMID COMPANY (US) | 1999-07-27 | — | — | US | disclosed |