Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | HTR1D | P28221 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7318081 | 0.86 | NFKB1 (0.48) | NFKB1NFKB2RELAHTR6 | |
| SCHEMBL7323697 | 0.84 | HTR1A (0.61) | HTR1AHTR1DHTR6 | |
| SCHEMBL8845524 | 0.83 | DRD2 (0.59) | HTR1AHTR1D | |
| SCHEMBL7322671 | 0.82 | DRD2 (0.65) | — | |
| SCHEMBL7319400 | 0.82 | HTR1A (0.64) | HTR1AHTR1DHTR6 | |
| SCHEMBL7315046 | 0.81 | DRD2 (0.64) | HTR1AHTR1DHTR6 | |
| SCHEMBL8845097 | 0.81 | HTR6 (0.70) | HTR1AHTR1DHTR6 | |
| SCHEMBL8844943 | 0.81 | DRD2 (0.69) | HTR6 | |
| SCHEMBL8844838 | 0.79 | DRD2 (0.55) | HTR1AHTR1D | |
| SCHEMBL8844835 | 0.79 | HTR1A (0.52) | HTR1AHTR1DHTR6FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684039-A | Chroman-2-ylmethylamino derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-11-04 | — | — | US | disclosed |