Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 13/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29412737 | 1.00 | SIGMAR1 (0.47) | SIGMAR1TMEM97SLC18A3MAPTKDM4E | |
| SCHEMBL7326207 | 0.91 | SIGMAR1 (0.48) | SIGMAR1SLC18A3MAPTALDH1A1 | |
| SCHEMBL11632591 | 0.84 | SIGMAR1 (0.43) | SIGMAR1TMEM97MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11633835 | 0.79 | SIGMAR1 (0.46) | SIGMAR1TMEM97MAPTALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30343200 | 0.78 | SIGMAR1 (0.45) | SIGMAR1TMEM97MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7326682 | 0.76 | SIGMAR1 (0.57) | SIGMAR1TMEM97MAPTALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9152015 | 0.75 | SIGMAR1 (0.56) | SIGMAR1TMEM97MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8330350 | 0.75 | PYCR1 (0.45) | SIGMAR1TMEM97SLC18A3MAPTKDM4E | |
| SCHEMBL8330793 | 0.74 | NUDT1 (0.52) | SIGMAR1TMEM97MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7319768 | 0.74 | SLC6A4 (0.45) | SIGMAR1TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235791-B1 | USING CIS N-CYCLOHEXYL-N-ETHYL(3-(3-CHLORO-CYCLOHEXYLPHENYL)ALLYL)AMINE | SANOFI-SYNTHELABO (FR) | 2001-05-22 | — | — | US | disclosed |