Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31153832 | 0.90 | L3MBTL1 (0.43) | CCR6PAX8ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL782973 | 0.90 | ALDH1A1 (0.47) | CCR6PAX8ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL3508186 | 0.89 | L3MBTL1 (0.44) | CCR6PAX8ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL1554957 | 0.88 | CCR6 (0.44) | CCR6PAX8ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL12722685 | 0.86 | CTSL (0.44) | CCR6PAX8ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL782974 | 0.86 | ALDH1A1 (0.44) | CCR6PAX8ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL19189188 | 0.86 | CCR6 (0.49) | CCR6PAX8ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL26749289 | 0.85 | ALDH1A1 (0.50) | CCR6PAX8ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL3212998 | 0.85 | CCR6 (0.45) | CCR6PAX8ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL8543386 | 0.84 | CCR6 (0.47) | CCR6PAX8ALDH1A1L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111372585-A | Degradants and degreddeterminants for target protein degradation | C4医药公司 | 2020-07-03 | — | — | CN | disclosed |
| US-5470849-A | Anticoagulants | SMITHKLINE BEECHAM CORP. (US) | 1995-11-28 | — | — | US | disclosed |
| EP-0557406-A4 | -G(G)-TURN PEPTIDOMIMETICS AS FIBRINOGEN ANTAGONISTS | — | 1993-10-06 | — | — | EP | disclosed |
| EP-0557406-A1 | GAMMA-TURN PEPTIDOMIMETICS AS FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-09-01 | — | — | EP | disclosed |
| WO-1992007568-A1 | η-TURN PEPTIDOMIMETICS AS FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-05-14 | — | — | WO | disclosed |