Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL782973 | 0.96 | ALDH1A1 (0.47) | ALDH1A1CCR6PAX8L3MBTL1MAPK1 | |
| SCHEMBL12722685 | 0.92 | CTSL (0.44) | ALDH1A1CCR6PAX8L3MBTL1MAPK1 | |
| SCHEMBL8543386 | 0.87 | CCR6 (0.47) | ALDH1A1CCR6PAX8L3MBTL1MAPK1 | |
| SCHEMBL7320141 | 0.86 | CCR6 (0.43) | ALDH1A1CCR6PAX8L3MBTL1MAPK1 | |
| SCHEMBL29144368 | 0.86 | ALDH1A1 (0.41) | ALDH1A1CCR6PAX8L3MBTL1MAPK1 | |
| SCHEMBL801192 | 0.85 | CCR6 (0.54) | ALDH1A1CCR6PAX8L3MBTL1MAPK1 | |
| SCHEMBL13721704 | 0.85 | HDAC3 (0.47) | ALDH1A1CCR6PAX8L3MBTL1MAPK1 | |
| SCHEMBL3508186 | 0.85 | L3MBTL1 (0.44) | ALDH1A1CCR6PAX8L3MBTL1MAPK1 | |
| SCHEMBL7294052 | 0.85 | L3MBTL1 (0.44) | ALDH1A1CCR6PAX8L3MBTL1MAPK1 | |
| SCHEMBL3171215 | 0.85 | ALDH1A1 (0.40) | ALDH1A1CCR6PAX8L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120070856-A1 | CROSS-LINKING AGENTS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120070856-A1 | CROSS-LINKING AGENTS | ORC3, TXN, PROC | ALDH1A1 2055/4885CCR6 2157/4885PAX8 1203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.