Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319186 | 0.97 | HPGD (0.36) | HPGDSIRT5BACE1ALDH1A1RAB9A | |
| SCHEMBL7317910 | 0.86 | MAPT (0.37) | ALDH1A1RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL7316032 | 0.84 | SIRT3 (0.41) | ALDH1A1RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL7310463 | 0.82 | SIRT3 (0.39) | ALDH1A1RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL10377207 | 0.81 | LMNA (0.40) | SIRT5BACE1ALDH1A1PDE3BPDE3A | |
| SCHEMBL10377206 | 0.78 | ALDH1A1 (0.38) | HPGDSIRT5BACE1ALDH1A1PDE3B | |
| SCHEMBL7320149 | 0.76 | ALDH1A1 (0.35) | HPGDSIRT5BACE1ALDH1A1RAB9A | |
| SCHEMBL7320153 | 0.76 | RAB9A (0.48) | HPGDALDH1A1PDE3BPDE3AP2RY12 | |
| SCHEMBL7311801 | 0.75 | SMN1; SMN2 (0.41) | SIRT5BACE1ALDH1A1RAB9AKDM4E | |
| SCHEMBL7320429 | 0.74 | KDM4E (0.45) | HPGDSIRT5BACE1ALDH1A1PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |