Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | REN | P00797 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 8/20 | 0.34 |
| ▸ | CNR1 | P21554 | 6/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316032 | 0.97 | SIRT3 (0.41) | SIRT3MAPTRENALDH1A1KDM4E | |
| SCHEMBL7319186 | 0.84 | HPGD (0.36) | MAPTRENALDH1A1KDM4ENPC1 | |
| SCHEMBL7317910 | 0.83 | MAPT (0.37) | MAPTRENALDH1A1KDM4ENPC1 | |
| SCHEMBL7320164 | 0.82 | HPGD (0.37) | MAPTRENALDH1A1KDM4ENPC1 | |
| SCHEMBL7310467 | 0.78 | ALDH1A1 (0.48) | MAPTALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL7316010 | 0.77 | ALDH1A1 (0.36) | MAPTRENALDH1A1KDM4ENPC1 | |
| SCHEMBL7315018 | 0.76 | REN (0.33) | REN | |
| SCHEMBL7307610 | 0.75 | SIRT3 (0.38) | SIRT3MAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL7316021 | 0.75 | ALDH1A1 (0.49) | MAPTALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL7308539 | 0.73 | SIRT3 (0.52) | SIRT3MAPTALDH1A1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |