Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.70 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.69 |
| ▸ | MMP9 | P14780 | 8/20 | 0.57 |
| ▸ | MMP13 | P45452 | 8/20 | 0.57 |
| ▸ | MMP2 | P08253 | 4/20 | 0.57 |
| ▸ | MMP8 | P22894 | 4/20 | 0.57 |
| ▸ | MMP12 | P39900 | 3/20 | 0.57 |
| ▸ | MMP14 | P50281 | 3/20 | 0.57 |
| ▸ | MMP16 | P51512 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | MMP1 | P03956 | 6/20 | 0.54 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.54 |
| ▸ | MMP3 | P08254 | 2/20 | 0.54 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.53 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.53 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5159892 | 0.87 | FFAR4 (0.74) | FFAR4ADAM17LMNAKEAP1CYTH2 | |
| SCHEMBL7322031 | 0.87 | FFAR4 (0.74) | FFAR4ADAM17LMNAKEAP1CYTH2 | |
| SCHEMBL7323556 | 0.84 | MMP13 (0.66) | FFAR4ADAM17MMP9MMP13MMP2 | |
| SCHEMBL12200992 | 0.82 | KCNA5 (0.60) | FFAR4ADAM17LMNAKEAP1CYTH2 | |
| SCHEMBL7322545 | 0.81 | FFAR4 (0.65) | FFAR4ADAM17LMNAKEAP1CYTH2 | |
| SCHEMBL7320157 | 0.78 | MMP13 (0.55) | FFAR4ADAM17MMP9MMP13MMP2 | |
| SCHEMBL7452155 | 0.76 | MMP13 (0.48) | FFAR4ADAM17MMP9MMP13MMP2 | |
| SCHEMBL7312055 | 0.75 | LMNA (0.65) | FFAR4LMNAKEAP1CYTH2ALDH1A1 | |
| SCHEMBL7308859 | 0.75 | FFAR4 (0.74) | FFAR4LMNACYTH2GABRG2GABRB3 | |
| SCHEMBL8627655 | 0.75 | KEAP1 (0.67) | FFAR4LMNAKEAP1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929097-A | INHIBIT TUMOR NECROSIS FACTOR-ALPHA CONVERTING ENZYME | AMERICAN CYANAMID COMPANY (US) | 1999-07-27 | — | — | US | disclosed |