Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.43 |
| ▸ | EPOR | P19235 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324667 | 0.92 | ALOX5 (0.41) | ALOX5MGLL | |
| SCHEMBL10378291 | 0.88 | LTA4H (0.39) | LTA4HEPORALOX5 | |
| SCHEMBL7330268 | 0.88 | ERAP2 (0.37) | ALOX5LTB4R | |
| SCHEMBL7322402 | 0.87 | TPSAB1 (0.38) | EPOR | |
| SCHEMBL7329315 | 0.82 | ALOX5 (0.37) | ALOX5 | |
| SCHEMBL7324394 | 0.80 | TPSAB1 (0.40) | LMNA | |
| SCHEMBL7327734 | 0.80 | ALOX5 (0.32) | ALOX5 | |
| SCHEMBL7328746 | 0.79 | SYK (0.38) | ALOX5SIGMAR1 | |
| SCHEMBL7330559 | 0.79 | LTA4H (0.34) | LTA4HEPOR | |
| SCHEMBL7322873 | 0.79 | CES1 (0.35) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |