Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.37 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | SGMS1 | Q86VZ5 | 2/20 | 0.34 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324667 | 0.91 | ALOX5 (0.41) | ALOX5 | |
| SCHEMBL7330169 | 0.89 | ERAP2 (0.36) | ERAP2ERAP1ACHESGMS1SGMS2 | |
| SCHEMBL10377223 | 0.89 | ERAP2 (0.36) | ERAP2ERAP1ACHESGMS1SGMS2 | |
| SCHEMBL7320169 | 0.88 | LTA4H (0.43) | LTB4RALOX5 | |
| SCHEMBL7321467 | 0.84 | ERAP2 (0.35) | ERAP2ERAP1 | |
| Hydrochloric Acid SCHEMBL7330752 | 0.84 | ERAP2 (0.35) | ERAP2ERAP1 | |
| SCHEMBL7323122 | 0.82 | CA2 (0.34) | ERAP2ERAP1 | |
| SCHEMBL7329315 | 0.81 | ALOX5 (0.37) | ALOX5 | |
| SCHEMBL7330032 | 0.79 | ERAP2 (0.33) | ERAP2ERAP1SPHK1 | |
| SCHEMBL7328746 | 0.78 | SYK (0.38) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |