Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7330307 | 0.83 | MEN1 (0.39) | KDM4CMEN1KMT2AITGB1ITGA4 | |
| SCHEMBL10433458 | 0.81 | CREBBP (0.37) | KDM4CMEN1KMT2AITGB1ITGA4 | |
| SCHEMBL10433460 | 0.81 | CREBBP (0.37) | KDM4CMEN1KMT2AITGB1ITGA4 | |
| SCHEMBL17846160 | 0.79 | MEN1 (0.41) | KDM4CMEN1KMT2AITGB1ITGA4 | |
| SCHEMBL7097200 | 0.76 | EPHX1 (0.43) | KDM4CMEN1KMT2A | |
| SCHEMBL10433383 | 0.74 | KDM4C (0.39) | KDM4CMEN1KMT2AITGB1ITGA4 | |
| SCHEMBL7098095 | 0.74 | KDM4C (0.39) | KDM4CMEN1KMT2AITGB1ITGA4 | |
| SCHEMBL10433401 | 0.73 | KDM4C (0.39) | KDM4CMEN1KMT2AITGB1ITGA4 | |
| SCHEMBL10433363 | 0.73 | EPHX1 (0.51) | KDM4CMEN1KMT2AITGB1ITGA4 | |
| SCHEMBL7050550 | 0.72 | SIGMAR1 (0.39) | KDM4CMEN1KMT2AITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |