Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.45 |
| ▸ | CMA1 | P23946 | 15/20 | 0.45 |
| ▸ | ELANE | P08246 | 3/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | CTRC | Q99895 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322063 | 0.91 | MALT1 (0.45) | MALT1CMA1ELANECTRC | |
| SCHEMBL10791046 | 0.91 | CMA1 (0.49) | MALT1CMA1ELANECTRC | |
| SCHEMBL7317544 | 0.90 | MALT1 (0.43) | MALT1CMA1ELANECTRC | |
| SCHEMBL7314093 | 0.82 | CMA1 (0.51) | MALT1CMA1ELANEF2PRSS1 | |
| SCHEMBL7321341 | 0.82 | CMA1 (0.56) | MALT1CMA1ELANEF2PRSS1 | |
| SCHEMBL7314620 | 0.77 | CMA1 (0.53) | CMA1ELANECTRC | |
| SCHEMBL7314317 | 0.76 | ITGB3 (0.59) | MALT1CMA1F2PRSS1 | |
| SCHEMBL7324440 | 0.76 | MALT1 (0.59) | MALT1CMA1ELANE | |
| SCHEMBL7307515 | 0.74 | CMA1 (0.54) | MALT1CMA1F2PRSS1 | |
| SCHEMBL7314754 | 0.74 | MALT1 (0.53) | MALT1CMA1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4691007-A | HUMAN LEUKOCYTE ELASTASE INHIBITORS | ICI AMERICAS INC. (US) | 1987-09-01 | — | — | US | disclosed |
| US-4596789-A | Pharmaceuticals | ICI AMERICAS INC. (US) | 1986-06-24 | — | — | US | disclosed |
| EP-0124317-A2 | Proline derivatives | ICI AMERICAS INC. (US) | 1984-11-07 | — | — | EP | disclosed |