Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308723 | 0.88 | PKM (0.43) | ALDH1A1MCL1SMN1; SMN2NPC1LMNA | |
| SCHEMBL7312759 | 0.84 | ALDH1A1 (0.37) | ALDH1A1MCL1ALBBCL2PKM | |
| SCHEMBL7315475 | 0.77 | PKM (0.44) | ALDH1A1KDM4ESMN1; SMN2LMNARAB9A | |
| SCHEMBL7312087 | 0.75 | MCL1 (0.39) | MAPTALDH1A1MCL1KDM4ELMNA | |
| SCHEMBL7317051 | 0.74 | PDE3B (0.50) | ADORA3MAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7316056 | 0.72 | PDE3B (0.41) | ADORA3MAPTALDH1A1MCL1KDM4E | |
| SCHEMBL7316412 | 0.72 | MCL1 (0.34) | MAPTALDH1A1MCL1KDM4ESMN1; SMN2 | |
| SCHEMBL7316415 | 0.72 | MCL1 (0.36) | ALDH1A1MCL1KDM4EALBBCL2 | |
| SCHEMBL7311127 | 0.72 | ALDH1A1 (0.43) | MAPTALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL7315852 | 0.71 | PDE3B (0.54) | ADORA3MAPTALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4277479-A | ANTI-ASTHMATIC, HYPOTENSIVE, ANTI-ULCER, ANTIINFLAMMATORY, VASODILATION, ENZYME INHIBITORS, ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-07-07 | — | — | US | disclosed |