Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308723 | 0.88 | PKM (0.43) | PKMHTTNLRP3HSD11B1ALDH1A1 | |
| SCHEMBL7311731 | 0.83 | GRM5 (0.42) | ALDH1A1KMT2ASMN1; SMN2MEN1TSHR | |
| SCHEMBL7314477 | 0.81 | PPARA (0.45) | PKMHTTNLRP3HSD11B1ALDH1A1 | |
| SCHEMBL7312759 | 0.80 | ALDH1A1 (0.37) | PKMHTTNLRP3HSD11B1ALDH1A1 | |
| SCHEMBL7307627 | 0.79 | PDE3B (0.52) | HTTHSD11B1ALDH1A1KMT2ANPSR1 | |
| SCHEMBL7310025 | 0.79 | PKM (0.44) | PKMHTTNLRP3HSD11B1ALDH1A1 | |
| SCHEMBL7316133 | 0.78 | PDE3B (0.42) | ALDH1A1KMT2ANPSR1SMN1; SMN2MEN1 | |
| SCHEMBL7320366 | 0.77 | ADORA3 (0.35) | PKMHTTNLRP3HSD11B1ALDH1A1 | |
| SCHEMBL11707712 | 0.73 | KDM4E (0.61) | HTTALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL31240336 | 0.73 | CYP1A2 (0.47) | HTTALDH1A1KMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4277479-A | ANTI-ASTHMATIC, HYPOTENSIVE, ANTI-ULCER, ANTIINFLAMMATORY, VASODILATION, ENZYME INHIBITORS, ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-07-07 | — | — | US | disclosed |