Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312759 | 0.90 | ALDH1A1 (0.37) | PKMHTTNLRP3HSD11B1MCL1 | |
| SCHEMBL7320366 | 0.88 | ADORA3 (0.35) | PKMHTTNLRP3HSD11B1MCL1 | |
| SCHEMBL7315475 | 0.88 | PKM (0.44) | PKMHTTNLRP3HSD11B1ALDH1A1 | |
| SCHEMBL7312087 | 0.84 | MCL1 (0.39) | HTTMCL1ALDH1A1KMT2ATSHR | |
| SCHEMBL7316415 | 0.80 | MCL1 (0.36) | PKMMCL1ALDH1A1ALBBCL2 | |
| SCHEMBL7310025 | 0.80 | PKM (0.44) | PKMHTTNLRP3HSD11B1MCL1 | |
| SCHEMBL7317051 | 0.79 | PDE3B (0.50) | HTTHSD11B1ALDH1A1KMT2ATSHR | |
| SCHEMBL7314477 | 0.79 | PPARA (0.45) | PKMHTTNLRP3HSD11B1MCL1 | |
| SCHEMBL7316412 | 0.78 | MCL1 (0.34) | MCL1ALDH1A1KMT2ATSHRMEN1 | |
| SCHEMBL7316056 | 0.77 | PDE3B (0.41) | MCL1ALDH1A1KMT2ATSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4277479-A | ANTI-ASTHMATIC, HYPOTENSIVE, ANTI-ULCER, ANTIINFLAMMATORY, VASODILATION, ENZYME INHIBITORS, ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-07-07 | — | — | US | disclosed |