Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | HPGDS | O60760 | 1/20 | 0.45 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.43 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7325573 | 0.84 | CA12 (0.53) | ALDH1A1HPGDSALKBH2MAPTRAB9A | |
| SCHEMBL7322694 | 0.82 | MAPKAPK2 (0.48) | ALDH1A1HPGDSALKBH2MAPTRAB9A | |
| SCHEMBL30872607 | 0.82 | ALKBH2 (0.68) | ALDH1A1HPGDSALKBH2MAPTRAB9A | |
| SCHEMBL8085746 | 0.82 | HPGDS (0.68) | ALDH1A1HPGDSALKBH2MAPTRAB9A | |
| SCHEMBL7323051 | 0.80 | HPGDS (0.45) | ALDH1A1HPGDSALKBH2MAPTRAB9A | |
| SCHEMBL7320411 | 0.79 | ALDH1A1 (0.49) | ALDH1A1HPGDSALKBH2MAPTRAB9A | |
| SCHEMBL7326021 | 0.78 | ALDH1A1 (0.48) | ALDH1A1HPGDSALKBH2MAPTRAB9A | |
| SCHEMBL7321749 | 0.78 | CA12 (0.52) | ALDH1A1HPGDSALKBH2MAPTRAB9A | |
| SCHEMBL27166306 | 0.76 | NPC1 (0.48) | ALDH1A1HPGDSALKBH2MAPTRAB9A | |
| SCHEMBL15153223 | 0.75 | ATM (0.46) | ALDH1A1HPGDSALKBH2MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117715904-A | CDK2 degrading agents and uses thereof | 凯麦拉医疗公司 | 2024-03-15 | — | — | CN | disclosed |
| EP-4334307-A1 | CDK2 DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2024-03-13 | — | — | EP | disclosed |
| WO-2022236058-A1 | CDK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |
| US-6232290-B1 | FUNGICIDES AGAINST PNEUMOCYSTIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-15 | — | — | US | disclosed |
| EP-1053247-A1 | ANTIFUNGAL CYCLOHEXAPEPTIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-22 | — | — | EP | disclosed |
| WO-1999040108-A1 | NEW COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-12 | — | — | WO | disclosed |