Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH2 | Q6NS38 | 2/20 | 0.68 |
| ▸ | HPGDS | O60760 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320665 | 0.82 | ALDH1A1 (0.57) | ALKBH2HPGDSALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL70281 | 0.81 | ALKBH2 (1.00) | ALKBH2HPGDSEGLN1SMN1; SMN2NPC1 | |
| SCHEMBL31583669 | 0.81 | ALKBH1 (0.54) | ALKBH2HPGDSEGLN1 | |
| SCHEMBL27680338 | 0.80 | ALKBH2 (0.72) | ALKBH2HPGDSEGLN1HSD11B1NPC1 | |
| SCHEMBL2856651 | 0.80 | ALKBH2 (0.72) | ALKBH2HPGDSALDH1A1EGLN1HSD11B1 | |
| SCHEMBL2860260 | 0.80 | ALKBH2 (0.72) | ALKBH2HPGDSEGLN1NPC1RAB9A | |
| SCHEMBL2850367 | 0.80 | ALKBH2 (0.72) | ALKBH2HPGDSEGLN1HSD11B1NPC1 | |
| SCHEMBL2852078 | 0.80 | ALKBH2 (0.72) | ALKBH2HPGDSALDH1A1EGLN1KDM4E | |
| SCHEMBL15331859 | 0.79 | ALKBH2 (0.70) | ALKBH2HPGDSALDH1A1EGLN1KDM4E | |
| Hydrochloric Acid SCHEMBL16467067 | 0.79 | ALKBH2 (0.70) | ALKBH2HPGDSEGLN1HSD11B1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117715904-A | CDK2 degrading agents and uses thereof | 凯麦拉医疗公司 | 2024-03-15 | — | — | CN | disclosed |