SCHEMBL732093

SCHEMBL732093

O=C(O)C[C@H](NC(=O)OCc1ccccc1)C(=O)OC(=O)[C@H](CC(=O)O)NC(=O)OCc1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 20/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7166866 1.00 CASP1 (0.66) CASP1
SCHEMBL8085967 1.00 CASP1 (0.66) CASP1
SCHEMBL4280674 0.92 CASP1 (0.67) CASP1
SCHEMBL4280669 0.92 CASP1 (0.67) CASP1
SCHEMBL11366966 0.91 CASP1 (0.57) CASP1
SCHEMBL13724740 0.90 CASP1 (0.64) CASP1
SCHEMBL19695419 0.90 CASP1 (0.64) CASP1
SCHEMBL1067460 0.90 CASP1 (0.64) CASP1
SCHEMBL554032 0.89 CASP1 (0.67) CASP1
SCHEMBL376886 0.89 CASP1 (0.67) CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0334236-B1 Preparation of n-protected alpha-l-aspartyl-l-phenylalanine methyl ester MITSUI TOATSU CHEMICALS (JP) 1994-08-31 EP claimed
US-5302743-A Reacting N-protected L-aspartic anhydride with L-phenylalanine methyl ester salt in non-aqueous solvent MITSUI TOATSU CHEMICALS, INC. (JP) 1994-04-12 US claimed
EP-0334236-A2 Preparation of n-protected alpha-l-aspartyl-l-phenylalanine methyl ester MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-09-27 EP claimed
US-4824994-A Method for production of N-protected-alpha-L-aspartyl-L-phenylalanine methyl ester AJINOMOTO CO., INC. (JP) 1989-04-25 US claimed
JP-61063694-A None JP disclosed
JP-60075497-A None JP disclosed
JP-5230049-A None JP disclosed
JP-3038581-A None JP disclosed
JP-58167578-A None JP disclosed
JP-58167577-A None JP disclosed
EP-4332227-B1 RNA CONTAINING MODIFIED NUCLEOSIDES AND METHODS OF USE THEREOF UNIV PENNSYLVANIA (US) 2026-02-11 EP disclosed
EP-4599852-A2 RNA CONTAINING MODIFIED NUCLEOSIDES AND METHODS OF USE THEREOF The Trustees of the University of Pennsylvania (US) 2025-08-13 EP disclosed
US-4508912-A UNING METAL OXIDE, HYDROXIDE, ACID OR ACID SALT, OR ORGANOBASIC COMPOUND CATALYST AJINOMOTO COMPANY, INCORPORATED (JP) 1985-04-02 US disclosed
US-4508912-A UNING METAL OXIDE, HYDROXIDE, ACID OR ACID SALT, OR ORGANOBASIC COMPOUND CATALYST AJINOMOTO COMPANY, INCORPORATED (JP) 1985-04-02 US disclosed
EP-0091330-A1 Process for the preparation of aspartame LABORATOIRES HUMAN PHARM S.A. (FR) 1983-10-12 EP disclosed
JP-S58167577-A PRODUCTION OF N-CARBOBENZOXY-L-ASPARTIC ANHYDRIDE AJINOMOTO CO INC 1983-10-03 JP disclosed
JP-S58167578-A PRODUCTION OF N-CARBOBENZOXY-L-ASPARTIC ANHYDRIDE AJINOMOTO CO INC 1983-10-03 JP disclosed
US-4175084-A AND AN N-ACYL ASPARTIC ACID CARRIER, FOR PSYCHOLOGICAL DISORDERS, LEARNING ENHANCEMENT AND SLEEP INDUCTION SENTRALINSTITUTT FOR INDUSTRIELL FORSKNING (NO) 1979-11-20 US disclosed
US-3959245-A SWEETENERS TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) 1976-05-25 US disclosed
JP-S06163694-A 0001-01-01 JP disclosed