Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.42 |
| ▸ | CPA1 | P15085 | 4/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CPA3 | P15088 | 2/20 | 0.34 |
| ▸ | CPB1 | P15086 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.34 |
| ▸ | MME | P08473 | 2/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | ECE1 | P42892 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9554926 | 0.91 | LTA4H (0.37) | LTA4H | |
| SCHEMBL7321089 | 0.83 | LTA4H (0.40) | LTA4HCPA1MMP2MMP9CYP1A2 | |
| SCHEMBL9554651 | 0.80 | CPB2 (0.42) | LTA4HCPA1CPB2MMEECE1 | |
| SCHEMBL9727512 | 0.80 | MME (0.47) | LTA4HMMP2MMP9MME | |
| SCHEMBL7379297 | 0.78 | ACE (0.48) | — | |
| SCHEMBL9740972 | 0.77 | POLB (0.31) | — | |
| SCHEMBL7269757 | 0.75 | BIRC2 (0.49) | — | |
| SCHEMBL8524822 | 0.75 | NLN (0.39) | CPA1MMP2MMP9MME | |
| SCHEMBL8524821 | 0.75 | NLN (0.39) | CPA1MMP2MMP9MME | |
| SCHEMBL31690300 | 0.74 | CYP1A2 (0.61) | CPA1CYP1A2CPA3CPB1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250517-A | Hypotensive and cardiotonic agents; cardiac insufficiency | HOFFMANN-LA ROCHE INC. (US) | 1993-10-05 | — | — | US | disclosed |
| EP-0310918-A2 | Peptide-like amino-acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1989-04-12 | — | — | EP | disclosed |