Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 6/20 | 0.41 |
| ▸ | REN | P00797 | 2/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | CHRND | Q07001 | 5/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.35 |
| ▸ | CHRNG | P07510 | 1/20 | 0.35 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | IL1RN | P18510 | 1/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.35 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7325341 | 0.96 | CTSD (0.39) | CTSDREN | |
| SCHEMBL7325118 | 0.91 | CTSD (0.50) | CTSDRENCTRB1 | |
| SCHEMBL7328982 | 0.88 | CTSD (0.41) | CTSDRENGRIA1CHRNDCHRNA1 | |
| SCHEMBL7329691 | 0.87 | CTSD (0.47) | CTSDRENCTRB1 | |
| SCHEMBL7323826 | 0.83 | REN (0.46) | CTSDREN | |
| SCHEMBL7321304 | 0.80 | CTSD (0.59) | CTSDREN | |
| SCHEMBL7326624 | 0.79 | CTSD (0.47) | CTSDREN | |
| SCHEMBL7357139 | 0.79 | CTSD (0.45) | CTSDREN | |
| SCHEMBL7327920 | 0.79 | CTSD (0.45) | CTSDREN | |
| SCHEMBL7326637 | 0.79 | CTSD (0.47) | CTSDREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |