Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 3/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.37 |
| ▸ | NPY1R | P25929 | 2/20 | 0.37 |
| ▸ | NPY4R | P50391 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.37 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322162 | 0.96 | CTSD (0.41) | CTSDREN | |
| SCHEMBL7329691 | 0.91 | CTSD (0.47) | CTSDBACE1REN | |
| SCHEMBL7328982 | 0.90 | CTSD (0.41) | CTSDREN | |
| SCHEMBL7325118 | 0.87 | CTSD (0.50) | CTSDREN | |
| SCHEMBL7323826 | 0.85 | REN (0.46) | CTSDBACE1REN | |
| SCHEMBL7327920 | 0.83 | CTSD (0.45) | CTSDBACE1REN | |
| SCHEMBL7357139 | 0.83 | CTSD (0.45) | CTSDBACE1BACE2REN | |
| SCHEMBL7326624 | 0.83 | CTSD (0.47) | CTSDBACE1BACE2REN | |
| SCHEMBL7326637 | 0.83 | CTSD (0.47) | CTSDBACE1BACE2REN | |
| SCHEMBL7328794 | 0.82 | REN (0.48) | CTSDBACE1REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |