SCHEMBL73224

SCHEMBL73224

NCn1cnc2ccccc21

nearest known ligand 0.73

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.70
CYP11B1 P15538 6/20 0.61
CYP11B2 P19099 6/20 0.61
TNF P01375 1/20 0.61
LMNA P02545 5/20 0.58
SMN1; SMN2 Q16637 4/20 0.58
HTT P42858 4/20 0.58
MAPK1 P28482 1/20 0.56
TSHR P16473 2/20 0.56
KDM4E B2RXH2 1/20 0.56
NPC1 O15118 1/20 0.56
ALOX15 P16050 1/20 0.56
EGLN3 Q9H6Z9 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
NPSR1 Q6W5P4 1/20 0.51
PKM P14618 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6879470 0.98 TDP1 (0.68) TDP1CYP11B1CYP11B2TNFLMNA
Hydrochloric Acid SCHEMBL6093960 0.98 TDP1 (0.68) TDP1CYP11B1CYP11B2TNFLMNA
Hydrochloric Acid SCHEMBL6946175 0.96 TDP1 (0.66) TDP1CYP11B1CYP11B2TNFLMNA
SCHEMBL86384 0.85 TDP1 (0.72) TDP1CYP11B1CYP11B2TNFLMNA
SCHEMBL825596 0.84 TDP1 (0.78) TDP1CYP11B1CYP11B2TNFLMNA
SCHEMBL6851027 0.83 TDP1 (0.70) TDP1CYP11B1CYP11B2TNFLMNA
SCHEMBL131657 0.83 TDP1 (0.70) TDP1CYP11B1CYP11B2TNFLMNA
SCHEMBL3161153 0.83 TDP1 (0.84) TDP1CYP11B1CYP11B2TNFLMNA
SCHEMBL30294105 0.83 TDP1 (0.84) TDP1CYP11B1CYP11B2TNFLMNA
SCHEMBL9814242 0.83 TDP1 (0.84) TDP1CYP11B1CYP11B2TNFLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240238176-A1 ANTI-POLLUTION ECO-FRIENDLY MATERIAL AND METHOD FOR PREPARING THE SAME Research & Business Foundation Sungkyunkwan University (KR) 2024-07-18 US claimed
EP-3037166-A1 ASYMMETRIC POROUS ADSORPTIVE BEAD EMD Millipore Corporation (US) 2016-06-29 EP claimed
US-9295928-B2 Porous adsorptive or chromatographic media EMD MILLIPORE CORPORATION (US) 2016-03-29 US claimed
WO-2016029146-A1 SPECIFIC INHIBITORS OF METHIONYL-TRNA SYNTHETASE UNIVERSITY OF WASHINGTON (US) 2016-02-25 WO claimed
US-20150060342-A1 Porous Adsorptive Or Chromatographic Media EMD MILLIPORE CORP (US) 2015-03-05 US claimed
US-8697847-B2 Protein purification using HCIC and ion exchange chromatography MEDAREX, L.L.C. (US) 2014-04-15 US claimed
US-20120165511-A1 PROTEIN PURIFICATION USING HCIC AND ION EXCHANGE CHROMATOGRAPHY MEDAREX, INC. 2012-06-28 US claimed
US-8158196-B2 Method of forming coated structures EMD MILLIPORE CORPORATION (US) 2012-04-17 US claimed
US-20110244127-A1 METHOD OF FORMING COATED STRUCTURES MILLIPORE CORPORATION (US) 2011-10-06 US claimed
US-20110049042-A1 Porous adsorptive or chromatographic media MILLIPORE CORPORATION (US) 2011-03-03 US claimed
US-5457096-A Antibiotic AMERICAN CYANAMID COMPANY (US) 1995-10-10 US claimed
US-5442059-A Antibiotics for mammalian and veterninary diseases AMERICAN CYANAMID COMPANY (US) 1995-08-15 US claimed
US-5420272-A 7-(substituted)-8-(substituted)-9-](substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines AMERICAN CYANAMID COMPANY (US) 1995-05-30 US claimed
EP-0618190-A1 9-[(Substituted glycyl)amido]-6-(substituted)-5-hydroxy-6-deoxytetracyclines AMERICAN CYANAMID COMPANY (US) 1994-10-05 EP claimed
US-5328902-A Antibiotics AMERICAN CYANAMID CO. (US) 1994-07-12 US claimed
EP-0582788-A1 7-(Substituted)-9- (substituted glycyl)-amido)-6-demethyl-6-deoxytetracyclines AMERICAN CYANAMID COMPANY (US) 1994-02-16 EP claimed
EP-0582789-A1 Novel 7-(substituted)-8-(substituted)-9- (substituted glycyl)amido -6-demethyl-6-deoxytetracyclines AMERICAN CYANAMID COMPANY (US) 1994-02-16 EP claimed
EP-0582829-A1 9-(substituted glycyl) amido - 6-demethyl-6-deoxytetracyclines as antibiotic agents AMERICAN CYANAMID COMPANY (US) 1994-02-16 EP claimed
EP-0578745-A1 PHOSPHORUS CONTAINING COMPOUNDS AS INHIBITORS OF RETROVIRUSES THE UPJOHN COMPANY (US) 1994-01-19 EP claimed
WO-1992017490-A1 PHOSPHORUS CONTAINING COMPOUNDS AS INHIBITORS OF RETROVIRUSES THE UPJOHN COMPANY (US) 1992-10-15 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240238176-A1 ANTI-POLLUTION ECO-FRIENDLY MATERIAL AND METHOD FOR PREPARING THE SAME CUTA, EXOSC9, EXOSC10 TDP1 1890/4885CYP11B1 3816/4885CYP11B2 4055/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.