SCHEMBL732255

SCHEMBL732255

c1cc(OCC2CO2)ccc1COCC1CO1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.59
ALDH1A1 P00352 4/20 0.56
TSHR P16473 4/20 0.56
TP53 P04637 3/20 0.56
MAPT P10636 2/20 0.56
HPGD P15428 2/20 0.56
HIF1A Q16665 2/20 0.56
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
PKM P14618 2/20 0.56
LMNA P02545 2/20 0.56
CYP1A2 P05177 1/20 0.56
PPARG P37231 1/20 0.56
GAA P10253 1/20 0.56
SMN1; SMN2 Q16637 2/20 0.53
CYP3A4 P08684 1/20 0.53
GLA P06280 1/20 0.42
DRD4 P21917 3/20 0.40
FGFR1 P11362 1/20 0.39
SRC P12931 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18548800 1.00 TDP1 (0.59) TDP1ALDH1A1TSHRTP53MAPT
SCHEMBL22322509 0.91 TDP1 (0.58) TDP1ALDH1A1TSHRTP53MAPT
SCHEMBL29615642 0.91 TDP1 (0.58) TDP1ALDH1A1TSHRTP53MAPT
SCHEMBL5634061 0.89 TDP1 (0.63) TDP1ALDH1A1TSHRTP53MAPT
SCHEMBL731016 0.89 TSHR (0.48) TDP1ALDH1A1TSHRTP53MAPT
SCHEMBL1228760 0.87 TDP1 (0.57) TDP1MAPTHIF1AMEN1KMT2A
SCHEMBL7294548 0.85 ALDH1A1 (0.53) TDP1ALDH1A1TSHRTP53MAPT
SCHEMBL20677146 0.84 TDP1 (0.79) TDP1ALDH1A1TSHRTP53MAPT
SCHEMBL21094081 0.84 TDP1 (0.79) TDP1ALDH1A1TSHRTP53MAPT
SCHEMBL50264 0.84 TDP1 (0.79) TDP1ALDH1A1TSHRTP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2788398-B1 SULFIDE EXTENDED EPOXY RESINS AND BARRIER COATINGS APPLICATIONS THEREOF SUN CHEMICAL CORP (US) 2018-07-25 EP claimed
US-9624380-B2 Sulfide extended epoxy resins and barrier coating applications thereof SUN CHEMICAL CORPORATION (US) 2017-04-18 US claimed
US-20140370220-A1 OVERPRINT VARNISHES WITH NON-AQUOUS DISPERSIONS SUN CHEMICAL CORPORATION (US) 2014-12-18 US claimed
US-20140342091-A1 SULFIDE EXTENDED EPOXY RESINS AND BARRIER COATING APPLICATIONS THEREOF SUN CHEMICAL CORPORATION (US) 2014-11-20 US claimed
WO-2024044505-A1 ADHESIVE COMPOSITION ZYMERGEN INC. (US) 2024-02-29 WO disclosed
EP-3094699-B1 COMBINATION OF CORK / POLYEPOXIDE BINDER AND METHOD FOR MANUFACTURING SAME DIAM BOUCHAGE (FR) 2019-02-06 EP disclosed
EP-2788398-B1 SULFIDE EXTENDED EPOXY RESINS AND BARRIER COATINGS APPLICATIONS THEREOF SUN CHEMICAL CORP (US) 2018-07-25 EP disclosed
US-20180142137-A1 AGGREGATING COMPOSITIONS, MODIFIED PARTICULATE SOLID COMPOSITIONS, AND METHODS FOR MAKING AND USING SAME THE LUBRIZOL CORPORATION 2018-05-24 US disclosed
EP-3238750-A1 ORTHOTIC DEVICE MADE OF NATURAL FIBRES AND A POLYEPOXIDE RESIN WITHOUT BISPHENOL A, IN PARTICULAR BIOSOURCED C.O.P. (FR) 2017-11-01 EP disclosed
US-9624380-B2 Sulfide extended epoxy resins and barrier coating applications thereof SUN CHEMICAL CORPORATION (US) 2017-04-18 US disclosed
WO-2015107114-A1 COMBINATION OF CORK / POLYEPOXIDE BINDER AND METHOD FOR MANUFACTURING SAME DIAM BOUCHAGE (FR) 2015-07-23 WO disclosed
WO-2015107113-A1 COMBINATION OF CORK / POLYHYDROXYURETHANE BINDER AND METHOD FOR MANUFACTURING SAME DIAM BOUCHAGE (FR) 2015-07-23 WO disclosed
US-20110152492-A1 Polymer Compositions and Methods of Making and Using Same POLYMERIGHT, INC. (US) 2011-06-23 US disclosed
US-7910666-B2 Mercaptan-hardened epoxy polymer compositions and processes for making and using same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2011-03-22 US disclosed
WO-2011008480-A1 POLYMER COMPOSITIONS AND METHODS OF MAKING AND USING SAME POLYMERIGHT, INC. (US) 2011-01-20 WO disclosed
WO-2009132010-A1 METHODS AND SYSTEMS FOR MAKING THIOL COMPOUNDS FROM TERMINAL OLEFINIC COMPOUNDS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2009-10-29 WO disclosed
US-20090264669-A1 Methods and Systems for Making Thiol Compounds from Terminal Olefinic Compounds CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2009-10-22 US disclosed
EP-1940992-A1 MERCAPTAN-HARDENED EPOXY POLYMER COMPOSITIONS AND PROCESSES FOR MAKING AND USING SAME Chevron Phillips Chemical Company LP (US) 2008-07-09 EP disclosed
US-20070112100-A1 MERCAPTAN-HARDENED EPOXY POLYMER COMPOSITIONS AND PROCESSES FOR MAKING AND USING SAME CHEVRON PHILLIPS CHEMICAL COMPANY, LP 2007-05-17 US disclosed
WO-2007022217-A1 MERCAPTAN-HARDENED EPOXY POLYMER COMPOSITIONS AND PROCESSES FOR MAKING AND USING SAME CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2007-02-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090264669-A1 Methods and Systems for Making Thiol Compounds from Terminal Olefinic Compounds TST, HHAT, GSTO1 TDP1 2381/4885ALDH1A1 157/4885TSHR 4571/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.