Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 5/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 5/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.33 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.32 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322674 | 1.00 | SLC6A1 (0.38) | SLC6A1SLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL7319245 | 1.00 | SLC6A1 (0.38) | SLC6A1SLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL7319255 | 1.00 | SLC6A1 (0.38) | SLC6A1SLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL7326222 | 0.92 | KIF11 (0.39) | SLC6A1SLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL7326219 | 0.92 | KIF11 (0.39) | SLC6A1SLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL7322735 | 0.90 | NPSR1 (0.36) | SLC6A1SLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL7322744 | 0.90 | NPSR1 (0.36) | SLC6A1SLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL7323867 | 0.85 | KIF11 (0.44) | SLC6A1SLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL7317362 | 0.85 | KIF11 (0.44) | SLC6A1SLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL7317367 | 0.85 | KIF11 (0.44) | SLC6A1SLC1A3SLC1A2SLC1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999041227-A1 | TRICYCLIC COMPOUNDS AS GLYCINE TRANSPORT INHIBITORS | ALLELIX NEUROSCIENCE, INC. (US) | 1999-08-19 | — | — | WO | claimed |
| US-6162824-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | ALLELIX NEUROSCIENCE INC. | 2000-12-19 | — | — | US | disclosed |
| WO-1999041227-A1 | TRICYCLIC COMPOUNDS AS GLYCINE TRANSPORT INHIBITORS | ALLELIX NEUROSCIENCE, INC. (US) | 1999-08-19 | — | — | WO | disclosed |