Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.40 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326620 | 0.89 | KMT2A (0.39) | BACE1KMT2ACMA1MEN1ATM | |
| SCHEMBL7330516 | 0.78 | CDYL2 (0.47) | CDYL2CDYLBACE1KMT2ACMA1 | |
| SCHEMBL7323521 | 0.76 | CDYL2 (0.41) | CDYL2CDYLKMT2ACMA1MEN1 | |
| SCHEMBL30905085 | 0.72 | MME (0.55) | — | |
| SCHEMBL7330506 | 0.70 | CTSD (0.49) | CTSD | |
| SCHEMBL29876771 | 0.70 | MME (0.53) | BACE1 | |
| SCHEMBL30052830 | 0.69 | OPRD1 (0.53) | — | |
| SCHEMBL7329194 | 0.69 | CDYL2 (0.43) | CDYL2CDYLBACE1PSMB5CTSD | |
| SCHEMBL30123004 | 0.68 | BACE1 (0.52) | BACE1CTSD | |
| SCHEMBL30799965 | 0.68 | BACE1 (0.61) | BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | claimed |