Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 13/20 | 0.43 |
| ▸ | MMP13 | P45452 | 12/20 | 0.43 |
| ▸ | MMP1 | P03956 | 12/20 | 0.43 |
| ▸ | MMP12 | P39900 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 6/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 5/20 | 0.38 |
| ▸ | MMP8 | P22894 | 4/20 | 0.38 |
| ▸ | MMP14 | P50281 | 4/20 | 0.38 |
| ▸ | MMP16 | P51512 | 4/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319446 | 0.83 | MMP9 (0.49) | MMP9MMP13MMP1MMP12MMP2 | |
| SCHEMBL7319004 | 0.80 | MMP9 (0.48) | MMP9MMP13MMP1MMP12MMP2 | |
| SCHEMBL7311965 | 0.78 | MMP13 (0.47) | MMP9MMP13MMP1MMP12MMP2 | |
| SCHEMBL7316165 | 0.78 | MMP9 (0.48) | MMP9MMP13MMP1MMP12MMP2 | |
| SCHEMBL7323399 | 0.78 | MMP9 (0.49) | MMP9MMP13MMP1MMP12MMP2 | |
| SCHEMBL7317327 | 0.78 | MMP9 (0.46) | MMP9MMP13MMP1MMP12MMP2 | |
| SCHEMBL7323537 | 0.77 | MMP9 (0.52) | MMP9MMP13MMP1MMP12CYP1A2 | |
| SCHEMBL7315893 | 0.77 | MMP13 (0.47) | MMP9MMP13MMP1CYP1A2LTA4H | |
| SCHEMBL7325505 | 0.77 | MMP9 (0.46) | MMP9MMP13MMP1MMP12MMP2 | |
| SCHEMBL7321840 | 0.76 | MMP9 (0.44) | MMP9MMP13MMP1MMP12MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929097-A | INHIBIT TUMOR NECROSIS FACTOR-ALPHA CONVERTING ENZYME | AMERICAN CYANAMID COMPANY (US) | 1999-07-27 | — | — | US | disclosed |