Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 15/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17439398 | 0.91 | PDK2 (0.64) | PDK2MEN1GAAKMT2ACA1 | |
| SCHEMBL13185281 | 0.88 | PDK2 (0.55) | PDK2MEN1GAAKMT2A | |
| SCHEMBL7315127 | 0.85 | PDK2 (0.51) | PDK2MEN1GAAKMT2ACA1 | |
| SCHEMBL7315657 | 0.84 | PDK2 (0.51) | PDK2MEN1GAAKMT2A | |
| SCHEMBL17456241 | 0.81 | PDK2 (0.52) | PDK2MEN1GAAKMT2APARP1 | |
| SCHEMBL30177008 | 0.81 | PDK2 (0.55) | PDK2MEN1GAAKMT2AGPR3 | |
| SCHEMBL17471968 | 0.81 | PDK2 (0.59) | PDK2MEN1GAAKMT2ACA1 | |
| SCHEMBL18386005 | 0.79 | THRB (0.45) | PDK2MEN1KMT2A | |
| SCHEMBL813078 | 0.79 | THRB (0.52) | PDK2MEN1GAAKMT2A | |
| SCHEMBL30345614 | 0.79 | THRB (0.52) | PDK2MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6162824-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | ALLELIX NEUROSCIENCE INC. | 2000-12-19 | — | — | US | disclosed |