Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRHR | P34981 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7327497 | 0.85 | TRHR (0.52) | TRHR | |
| SCHEMBL7334617 | 0.85 | TRHR (0.52) | TRHR | |
| SCHEMBL7273227 | 0.80 | CYP2C9 (0.47) | DPP4ALDH1A1LMNADPP7 | |
| SCHEMBL10864928 | 0.77 | OPRM1 (0.43) | TRHRDPP4OPRM1 | |
| SCHEMBL29591738 | 0.76 | TRHR (0.46) | TRHROPRM1 | |
| SCHEMBL29630592 | 0.76 | TRHR (0.46) | TRHROPRM1 | |
| SCHEMBL5734357 | 0.76 | DPP4 (0.44) | DPP4LMNADPP7 | |
| SCHEMBL4595209 | 0.76 | DPP4 (0.44) | DPP4LMNADPP7 | |
| SCHEMBL4595206 | 0.76 | DPP4 (0.44) | DPP4LMNADPP7 | |
| SCHEMBL29649768 | 0.76 | OPRM1 (0.54) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384380-A2 | Novel peptide derivatives and their pharmaceutical use | JAPAN TOBACCO INC. (JP) | 1990-08-29 | — | — | EP | claimed |