SCHEMBL29649768

SCHEMBL29649768

N[C@@H](Cc1c[nH]cn1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 3/20 0.54
OPRD1 P41143 2/20 0.52
OPRK1 P41145 1/20 0.52
SLC6A2 P23975 1/20 0.51
REN P00797 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30456393 0.97 OPRM1 (0.55) OPRM1OPRD1OPRK1SLC6A2
SCHEMBL38652354 0.93 SLC6A2 (0.55) OPRM1OPRD1OPRK1SLC6A2REN
SCHEMBL29390515 0.92 OPRM1 (0.52) OPRM1OPRD1OPRK1SLC6A2REN
SCHEMBL30480492 0.91 OPRM1 (0.55) OPRM1OPRD1OPRK1SLC6A2REN
SCHEMBL30480493 0.91 OPRM1 (0.55) OPRM1OPRD1OPRK1SLC6A2REN
SCHEMBL31127558 0.91 F2 (0.60) OPRM1OPRD1OPRK1SLC6A2
SCHEMBL6516908 0.91 REN (0.58) OPRM1OPRD1OPRK1SLC6A2REN
SCHEMBL29525618 0.91 REN (0.58) OPRM1OPRD1OPRK1SLC6A2REN
SCHEMBL10522787 0.90 OPRM1 (0.53) OPRM1OPRD1OPRK1SLC6A2REN
SCHEMBL30729666 0.89 SLC6A2 (0.52) OPRM1OPRD1OPRK1SLC6A2REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026090251-A1 METHODS FOR IMPROVING TREATMENT OUTCOMES IN PATIENTS UNDERGOING ULTRAFILTRATION PROLETARIAT THERAPEUTICS, INC. (US) 2026-04-30 WO disclosed
US-20260060962-A1 METHODS AND AGENTS THAT STIMULATE MITOCHONDRIAL TURNOVER FOR TREATING DISEASE CAPACITY BIO INC (US) 2026-03-05 US disclosed
US-20250320471-A1 Method for Producing Compounds, Method for Producing Compound Library, Compound Library, and Screening Method UNIV TOKYO (JP) 2025-10-16 US disclosed
US-12343331-B2 Methods and agents that stimulate mitochondrial turnover for treating disease Capacity Bio, Inc. (US) 2025-07-01 US disclosed
EP-4337675-A1 ANGIOTENSIN-(1-9) ANALOGUE BASED ON D AMINO ACIDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF Universidad De Chile (CL) 2024-03-20 EP disclosed
EP-4284779-A1 METHODS AND AGENTS THAT STIMULATE MITOCHONDRIAL TURNOVER FOR TREATING DISEASE Capacity Bio, Inc. (US) 2023-12-06 EP disclosed
CN-117120417-A Methods and agents for stimulating mitochondrial turnover to treat diseases 容量生物公司 2023-11-24 CN disclosed
WO-2022238734-A1 ANGIOTENSIN-(1-9) ANALOGUE BASED ON D AMINO ACIDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF UNIVERSIDAD DE CHILE (CL) 2022-11-17 WO disclosed
WO-2022165189-A1 METHODS AND AGENTS THAT STIMULATE MITOCHONDRIAL TURNOVER FOR TREATING DISEASE Capacity Bio, Inc. (US) 2022-08-04 WO disclosed
US-20220233507-A1 METHODS AND AGENTS THAT STIMULATE MITOCHONDRIAL TURNOVER FOR TREATING DISEASE Capacity Bio, Inc. 2022-07-28 US disclosed
US-11331368-B2 Angiotensin receptor agonists and uses thereof MONASH UNIVERSITY (AU) 2022-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12343331-B2 Methods and agents that stimulate mitochondrial turnover for treating disease NLN, MAVS, PINK1 OPRM1 988/4885OPRD1 1329/4885OPRK1 938/4885
US-20220233507-A1 METHODS AND AGENTS THAT STIMULATE MITOCHONDRIAL TURNOVER FOR TREATING DISEASE NLN, MAVS, PINK1 OPRM1 988/4885OPRD1 1329/4885OPRK1 938/4885
US-20260060962-A1 METHODS AND AGENTS THAT STIMULATE MITOCHONDRIAL TURNOVER FOR TREATING DISEASE MDH2, NLN, PINK1 OPRM1 3210/4885OPRD1 2958/4885OPRK1 3103/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.