Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | KLK1 | P06870 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7325116 | 1.00 | KMT2A (0.51) | KMT2AELANEMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL7322271 | 0.95 | KMT2A (0.47) | KMT2AELANEMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL7320565 | 0.82 | MAPT (0.54) | ELANEMAPTMAPK1KDM4EALDH1A1 | |
| SCHEMBL7328267 | 0.78 | KMT2A (0.50) | KMT2AELANEMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL3362024 | 0.77 | KMT2A (0.68) | KMT2AMAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL3362022 | 0.77 | KMT2A (0.68) | KMT2AMAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7333700 | 0.77 | ELANE (0.41) | ELANEMAPTMAPK1KDM4EKLK1 | |
| SCHEMBL7333102 | 0.77 | MAPT (0.48) | KMT2AELANEMAPTMAPK1KDM4E | |
| SCHEMBL7323689 | 0.76 | TNFRSF1A (0.64) | KMT2AMAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7323696 | 0.76 | TNFRSF1A (0.64) | KMT2AMAPTSMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4570006-A | ANTITHROMBIN; ENZYME AND HORMONE INHIBITORS | TORII & CO. LTD. (JP) | 1986-02-11 | — | — | US | disclosed |
| US-4514416-A | Amidine compound, process for producing same and anti-complement agent comprising same | TORII & CO. LTD. (JP) | 1985-04-30 | — | — | US | disclosed |