Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | PLAT | P00750 | 1/20 | 0.50 |
| ▸ | KLK1 | P06870 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.50 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3362024 | 1.00 | KMT2A (0.68) | KMT2AMAPTALDH1A1KDM4ETDP1 | |
| SCHEMBL7338984 | 0.89 | PLAU (0.63) | KMT2AMAPTALDH1A1KDM4ETDP1 | |
| SCHEMBL7338981 | 0.89 | PLAU (0.63) | KMT2AMAPTALDH1A1KDM4ETDP1 | |
| SCHEMBL11091261 | 0.86 | KMT2A (0.69) | KMT2AMAPTALDH1A1KDM4ETDP1 | |
| SCHEMBL11091258 | 0.86 | KMT2A (0.69) | KMT2AMAPTALDH1A1KDM4ETDP1 | |
| SCHEMBL11091252 | 0.86 | KMT2A (0.69) | KMT2AMAPTALDH1A1KDM4ETDP1 | |
| SCHEMBL10492940 | 0.85 | MAOB (0.54) | KMT2AMAPTALDH1A1KDM4ETDP1 | |
| SCHEMBL16982630 | 0.85 | KMT2A (0.83) | KMT2AMAPTALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL7341758 | 0.82 | FTO (0.56) | KMT2AMAPTALDH1A1KDM4ETDP1 | |
| Phenyl Cinnamate SCHEMBL1055160 | 0.82 | KMT2A (0.77) | KMT2AMAPTALDH1A1TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100009970-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | COMBINATORX (SINGAPORE) PTE. LTD. (SG) | 2010-01-14 | — | — | US | disclosed |
| US-20080161324-A1 | Compositions and methods for treatment of viral diseases | EXCRX (SINGAPORE) PTE. LTD. (F.K.A. COMBINATORX (SINGAPORE) PTE LTD.) (SG) | 2008-07-03 | — | — | US | disclosed |
| WO-2008033466-A2 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | COMBINATORX (SINGAPORE) PRE. LTD. (SG) | 2008-03-20 | — | — | WO | disclosed |
| US-4808405-A | ANTICOAGULANT | BEECHAM GROUP P.L.C. (GB) | 1989-02-28 | — | — | US | disclosed |
| EP-0151593-B1 | ENZYME DERIVATIVES | BEECHAM GROUP PLC (GB) | 1989-02-22 | — | — | EP | disclosed |
| US-4604285-A | ANTICOAGULANT | BEECHAM GROUP P.L.C. (GB) | 1986-08-05 | — | — | US | disclosed |
| EP-0151593-A1 | ENZYME DERIVATIVES. | BEECHAM GROUP PLC (GB) | 1985-08-21 | — | — | EP | disclosed |
| WO-1985000521-A1 | ENZYME DERIVATIVES | BEECHAM GROUP P.L.C. (GB) | 1985-02-14 | — | — | WO | disclosed |
| EP-0009879-B1 | ENZYME DERIVATIVES FOR USE IN THE TREATMENT OF VENOUS THROMBOSIS, COMPOSITIONS CONTAINING THEM AND THEIR PREPARATION | BEECHAM GROUP PLC (GB) | 1983-10-12 | — | — | EP | disclosed |
| EP-0028489-B1 | ENZYME DERIVATIVES, AND THEIR PREPARATION | BEECHAM GROUP PLC (GB) | 1983-10-05 | — | — | EP | disclosed |
| US-4337244-A | COMPRISING A FIBRINOLYTIC ENZYME BLOCKED BY AN END GROUP REMOVABLE BY HYDROLYSIS | BEECHAM GROUP LIMITED (GB) | 1982-06-29 | — | — | US | disclosed |
| US-4285932-A | Enzyme derivatives for use in the treatment of venous thrombosis | BEECHAM GROUP LIMITED (GB) | 1981-08-25 | — | — | US | disclosed |
| EP-0028489-A1 | Enzyme derivatives, and their preparation | BEECHAM GROUP PLC (GB) | 1981-05-13 | — | — | EP | disclosed |
| EP-0009879-A1 | Enzyme derivatives for use in the treatment of venous thrombosis, compositions containing them and their preparation | BEECHAM GROUP PLC (GB) | 1980-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009970-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | HTR1A, HTR3B, HTR3A | KMT2A 1108/4885MAPT 1527/4885ALDH1A1 2240/4885 |
| US-20080161324-A1 | Compositions and methods for treatment of viral diseases | HAVCR2, EIF2AK2, RNASE1 | KMT2A 2353/4885MAPT 3341/4885ALDH1A1 785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.