Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.53 |
| ▸ | F7 | P08709 | 1/20 | 0.47 |
| ▸ | FPR2 | P25090 | 6/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.44 |
| ▸ | TMPRSS15 | P98073 | 7/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307665 | 0.86 | ITGB3 (0.60) | ITGB3ITGA2BF7PRSS1TMPRSS15 | |
| SCHEMBL7321771 | 0.85 | ITGB3 (0.71) | ITGB3ITGA2B | |
| SCHEMBL7325186 | 0.83 | FPR2 (0.48) | FPR2CTSBMME | |
| SCHEMBL7304352 | 0.83 | ITGB3 (0.66) | ITGB3ITGA2B | |
| SCHEMBL7324926 | 0.83 | NOS2 (0.51) | FPR2MME | |
| SCHEMBL7331831 | 0.81 | ITGB3 (0.49) | ITGB3ITGA2BF7 | |
| Trifluoroacetic Acid SCHEMBL7308865 | 0.80 | ITGB3 (0.60) | ITGB3ITGA2B | |
| SCHEMBL7336254 | 0.79 | PRSS1 (0.50) | PRSS1TMPRSS15 | |
| SCHEMBL7327768 | 0.78 | ITGB3 (0.48) | ITGB3ITGA2BF7PRSS1TMPRSS15 | |
| SCHEMBL13744829 | 0.77 | ITGB3 (0.65) | ITGB3ITGA2BF7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5550159-A | Peptide mimics useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1996-08-27 | — | — | US | disclosed |
| US-5453440-A | Amidine functional group on benzene ring, anticoagulants | G. D. SEARLE & CO. (US) | 1995-09-26 | — | — | US | disclosed |
| WO-1993018058-A1 | PEPTIDES MIMICS USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1993-09-16 | — | — | WO | disclosed |