Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 5/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | NOS3 | P29474 | 2/20 | 0.47 |
| ▸ | NOS1 | P29475 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 2/20 | 0.45 |
| ▸ | EED | O75530 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 6/20 | 0.43 |
| ▸ | MME | P08473 | 2/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322068 | 0.93 | PPARG (0.47) | NOS2PPARGNOS3NOS1BACE1 | |
| SCHEMBL7321906 | 0.88 | MMP2 (0.43) | PPARG | |
| SCHEMBL7318683 | 0.88 | MMP2 (0.43) | PPARG | |
| SCHEMBL7321638 | 0.86 | PPARG (0.47) | NOS2PPARGNOS3NOS1EED | |
| SCHEMBL7324333 | 0.85 | NOS3 (0.45) | NOS2NOS3NOS1FPR2 | |
| Trifluoroacetic Acid SCHEMBL7327858 | 0.85 | MMP2 (0.41) | NOS2PPARGNOS3NOS1 | |
| SCHEMBL7329586 | 0.84 | HDAC3 (0.60) | — | |
| SCHEMBL7328374 | 0.84 | SMN1; SMN2 (0.46) | NOS2NOS3NOS1 | |
| SCHEMBL7330015 | 0.84 | MMP2 (0.42) | PPARG | |
| SCHEMBL7325178 | 0.83 | ITGB3 (0.53) | FPR2MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992018117-A1 | ANTI-THROMBOTIC PEPTIDE AND PSEUDOPEPTIDE DERIVATIVES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS), INC. (US) | 1992-10-29 | — | — | WO | disclosed |