Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.49 |
| ▸ | MC3R | P41968 | 6/20 | 0.47 |
| ▸ | MC4R | P32245 | 5/20 | 0.47 |
| ▸ | MC5R | P33032 | 4/20 | 0.47 |
| ▸ | CA12 | O43570 | 5/20 | 0.43 |
| ▸ | CA2 | P00918 | 5/20 | 0.43 |
| ▸ | CA9 | Q16790 | 5/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7328587 | 0.83 | CYP3A4 (0.59) | TSHR | |
| SCHEMBL7320232 | 0.78 | REN (0.55) | RENMC3RMC4R | |
| SCHEMBL7327795 | 0.77 | REN (0.53) | RENMC3RMC4RMC5R | |
| SCHEMBL7321088 | 0.76 | CA12 (0.70) | CA12CA2CA9CA1CA3 | |
| SCHEMBL21498143 | 0.73 | REN (0.55) | RENMC3RMC4RMC5R | |
| SCHEMBL7319791 | 0.72 | REN (0.50) | RENMC3RMC4RKDM4E | |
| SCHEMBL9098622 | 0.72 | CA12 (0.79) | CA12CA2CA9KDM4ETSHR | |
| SCHEMBL26087539 | 0.71 | CA12 (0.77) | CA12CA2CA9KDM4ETSHR | |
| SCHEMBL18096448 | 0.71 | CA12 (0.77) | CA12CA2CA9KDM4ETSHR | |
| SCHEMBL22566158 | 0.70 | MC3R (0.58) | RENMC3RMC4RMC5RCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5218000-A | Nervous system disorders, antiischemic agents | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1993-06-08 | — | — | US | disclosed |
| EP-0361687-A1 | Therapeutic polyamine-amides | BTG INTERNATIONAL LIMITED (GB) | 1990-04-04 | — | — | EP | disclosed |
| WO-1990002114-A1 | THERAPEUTIC POLYAMINE-AMIDES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1990-03-08 | — | — | WO | disclosed |