Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 8/20 | 0.77 |
| ▸ | HTR1D | P28221 | 8/20 | 0.77 |
| ▸ | ICMT | O60725 | 1/20 | 0.64 |
| ▸ | HTR1A | P08908 | 7/20 | 0.61 |
| ▸ | HTR2C | P28335 | 4/20 | 0.61 |
| ▸ | HTR1B | P28222 | 5/20 | 0.60 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | HTR7 | P34969 | 2/20 | 0.59 |
| ▸ | HTR6 | P50406 | 2/20 | 0.59 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.59 |
| ▸ | HTR2B | P41595 | 2/20 | 0.59 |
| ▸ | MPO | P05164 | 1/20 | 0.59 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.59 |
| ▸ | HTR3B | O95264 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | DRD1 | P21728 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30867163 | 0.87 | HTR1D (1.00) | HTR2AHTR1DHTR1AHTR2CHTR1B | |
| SCHEMBL1129793 | 0.87 | HTR1D (1.00) | HTR2AHTR1DHTR1AHTR2CHTR1B | |
| SCHEMBL2536567 | 0.86 | LTA4H (0.67) | HTR2AHTR1DHTR1AHTR2CHTR1B | |
| Iodide SCHEMBL27075559 | 0.86 | HTR1D (0.97) | HTR2AHTR1DHTR1AHTR2CHTR1B | |
| Hydrochloric Acid SCHEMBL892927 | 0.86 | HTR2A (0.97) | HTR2AHTR1DHTR1AHTR2CHTR1B | |
| SCHEMBL7322600 | 0.85 | HTR2A (0.77) | HTR2AHTR1DHTR1AHTR2CHTR1B | |
| SCHEMBL2537905 | 0.85 | MPO (0.77) | HTR2AHTR1DHTR1AHTR2CHTR1B | |
| SCHEMBL7331404 | 0.84 | HTR1A (0.79) | HTR2AHTR1DHTR1AHTR2CHTR1B | |
| Cyanide SCHEMBL28696057 | 0.83 | HTR1D (0.91) | HTR2AHTR1DHTR1AHTR2CHTR1B | |
| SCHEMBL7324823 | 0.82 | HTR1D (0.68) | HTR2AHTR1DICMTHTR1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674620-A1 | TRYPTAMINE ANALOGUES AS 5-HT 1?-LIKE AGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-10-04 | — | — | EP | claimed |
| WO-1994014771-A1 | TRYPTAMINE ANALOGUES AS 5-HT1-LIKE AGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-07-07 | — | — | WO | claimed |
| EP-0674620-A1 | TRYPTAMINE ANALOGUES AS 5-HT 1?-LIKE AGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014771-A1 | TRYPTAMINE ANALOGUES AS 5-HT1-LIKE AGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-07-07 | — | — | WO | disclosed |