Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | METAP1 | P53582 | 2/20 | 0.46 |
| ▸ | F12 | P00748 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326180 | 0.81 | ALDH1A1 (0.54) | MAPTKDM4EMAPK1ALDH1A1HPGD | |
| SCHEMBL7233586 | 0.80 | MAPT (0.53) | MAPTKDM4EMAPK1ALDH1A1HPGD | |
| SCHEMBL7242296 | 0.80 | PTGS2 (0.47) | MAPTKDM4EMAPK1ALDH1A1METAP1 | |
| SCHEMBL7312377 | 0.79 | MAPT (0.40) | MAPTKDM4EMAPK1ALDH1A1HPGD | |
| SCHEMBL30795240 | 0.75 | HTT (0.55) | MAPTKDM4EALDH1A1METAP1F12 | |
| SCHEMBL3924704 | 0.75 | HTT (0.55) | MAPTKDM4EALDH1A1METAP1F12 | |
| SCHEMBL7319092 | 0.73 | PTGS1 (0.60) | MAPTPOLB | |
| SCHEMBL3519438 | 0.69 | ALDH1A1 (0.54) | MAPTKDM4EMAPK1ALDH1A1TDP1 | |
| SCHEMBL12074966 | 0.69 | KDM4E (0.45) | KDM4EMAPK1ALOX15TDP1METAP1 | |
| SCHEMBL1674090 | 0.69 | FLT3 (0.64) | MAPTALDH1A1METAP1F12GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010044445-A1 | AZOLE INHIBITORS OF CYTOKINE PRODUCTION | ABBOTT LABORATORIES | 2001-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010044445-A1 | AZOLE INHIBITORS OF CYTOKINE PRODUCTION | IL5, IL2, IL4 | MAPT 2674/4885KDM4E 2261/4885MAPK1 410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.