Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 8/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7325327 | 0.81 | MAPT (0.48) | ALDH1A1KDM4EMAPTHPGDALOX15 | |
| SCHEMBL7232487 | 0.77 | PTGS2 (0.46) | ALDH1A1KDM4EMAPTGRM5TSHR | |
| SCHEMBL7314421 | 0.76 | MAPT (0.45) | ALDH1A1KDM4EMAPTHPGDALOX15 | |
| SCHEMBL7234160 | 0.76 | KDM4E (0.58) | ALDH1A1KDM4EMAPTHPGDALOX15 | |
| SCHEMBL12074966 | 0.74 | KDM4E (0.45) | KDM4EALOX15MAPK1TDP1GRM5 | |
| SCHEMBL13860632 | 0.72 | RAB9A (0.59) | ALDH1A1KDM4EMAPTALOX15MAPK1 | |
| SCHEMBL12075336 | 0.69 | CCR1 (0.51) | ALDH1A1KDM4EMAPTALOX15MAPK1 | |
| SCHEMBL7319734 | 0.69 | PTGS2 (0.50) | ALDH1A1KDM4EMAPTHPGDALOX15 | |
| Dipyridyl SCHEMBL3368875 | 0.66 | KDM4E (0.70) | ALDH1A1KDM4EMAPTHPGDALOX15 | |
| SCHEMBL24404819 | 0.65 | KDM4E (0.50) | ALDH1A1KDM4EMAPTHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010044445-A1 | AZOLE INHIBITORS OF CYTOKINE PRODUCTION | ABBOTT LABORATORIES | 2001-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010044445-A1 | AZOLE INHIBITORS OF CYTOKINE PRODUCTION | IL5, IL2, IL4 | ALDH1A1 211/4885KDM4E 2261/4885MAPT 2674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.