Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4480328 | 0.79 | KMT2A (0.59) | SMN1; SMN2KMT2AMEN1FAAHCYP3A4 | |
| SCHEMBL7330210 | 0.74 | OPRM1 (0.48) | SMN1; SMN2KMT2AMEN1EPHX2CYP2C19 | |
| SCHEMBL19884743 | 0.73 | ALDH1A1 (0.60) | SMN1; SMN2KMT2AMEN1CYP2D6TSHR | |
| SCHEMBL2615238 | 0.72 | CD274 (0.92) | LMNASMN1; SMN2CD274EPHX2KDM4E | |
| SCHEMBL2615239 | 0.72 | CD274 (0.92) | LMNASMN1; SMN2CD274EPHX2KDM4E | |
| SCHEMBL21381650 | 0.71 | SLC6A3 (0.51) | CYP2D6SLC6A3 | |
| SCHEMBL4559188 | 0.71 | HTT (0.53) | CD274TSHR | |
| SCHEMBL26331426 | 0.71 | TSHR (0.53) | SMN1; SMN2KMT2AMEN1ATMCYP2D6 | |
| SCHEMBL3396988 | 0.70 | HTT (0.54) | LMNASMN1; SMN2KMT2AMEN1CD274 | |
| SCHEMBL7328218 | 0.70 | SLC6A3 (0.53) | CYP2D6SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4032642-A | SEDATIVES, TRANQUILIZERS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1977-06-28 | — | — | US | claimed |
| US-3956296-A | ANTIINFLAMMATORY, SEDATIVES, TRANQUILIZERS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1976-05-11 | — | — | US | claimed |