Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13873757 | 0.78 | EPHX2 (0.58) | OPRM1CYP2C9EPHX2MEN1KMT2A | |
| SCHEMBL13716041 | 0.77 | HSD11B1 (0.42) | TAS1R3TAS1R1EPHX2NAMPTCYP2C19 | |
| Hydrochloric Acid SCHEMBL4480328 | 0.77 | KMT2A (0.59) | CYP2C19SLC6A3SMN1; SMN2MEN1KMT2A | |
| SCHEMBL13873568 | 0.75 | EPHX2 (0.57) | CYP2C9EPHX2NAMPTCYP2C19HSD11B1 | |
| SCHEMBL13873546 | 0.74 | EPHX2 (0.57) | CYP2C9EPHX2NAMPTCYP2C19HSD11B1 | |
| SCHEMBL7325448 | 0.74 | LMNA (0.54) | EPHX2CYP2C19SLC6A3SMN1; SMN2MEN1 | |
| SCHEMBL13873509 | 0.74 | ALDH1A1 (0.50) | HTTEPHX2NAMPTHSD11B1SMN1; SMN2 | |
| SCHEMBL13125273 | 0.74 | POLB (0.54) | EPHX2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL13873617 | 0.73 | RAB9A (0.62) | CYP2C9EPHX2KMT2A | |
| SCHEMBL1313176 | 0.72 | DRD2 (0.57) | HTTCYP2C9NAMPTCYP2C19HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4032642-A | SEDATIVES, TRANQUILIZERS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1977-06-28 | — | — | US | claimed |
| US-3956296-A | ANTIINFLAMMATORY, SEDATIVES, TRANQUILIZERS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1976-05-11 | — | — | US | claimed |