SCHEMBL7327504

SCHEMBL7327504

CCCC[C@@H](C=O)NC(=O)[C@H](CC(C)C)NC(=O)CC(C)C

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CTSK P43235 14/20 0.54
CTSL P07711 3/20 0.40
CTSB P07858 3/20 0.40
BIRC2 Q13490 2/20 0.40
CTSH P09668 2/20 0.40
CTSS P25774 1/20 0.38
PSMB5 P28074 1/20 0.37
MMP3 P08254 1/20 0.37
MMP9 P14780 1/20 0.37
PLA2G10 O15496 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7335291 0.88 CTSK (0.53) CTSKCTSLCTSBPSMB5PLA2G10
SCHEMBL7379299 0.87 CTSK (0.52) CTSKPSMB5PLA2G10
SCHEMBL7335399 0.87 CTSK (0.52) CTSKPSMB5PLA2G10
SCHEMBL8972183 0.86 CTSK (0.57) CTSKCTSLCTSBCTSHCTSS
SCHEMBL8387889 0.86 CTSK (0.57) CTSKCTSLCTSBCTSHCTSS
SCHEMBL8695376 0.86 CTSK (0.57) CTSKCTSLCTSBCTSHCTSS
SCHEMBL5712420 0.86 CTSK (0.57) CTSKCTSLCTSBCTSHCTSS
SCHEMBL1783728 0.85 CTSK (0.56) CTSKCTSLCTSBBIRC2CTSH
SCHEMBL231491 0.85 CTSK (0.56) CTSKCTSLCTSBBIRC2CTSH
SCHEMBL258985 0.85 CTSK (0.56) CTSKCTSLCTSBBIRC2CTSH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5510531-A ANTIINFLAMMATROY AGENTS, MUSCULAR DISORDERS SUNTORY LIMITED (JP) 1996-04-23 US disclosed
EP-0393457-B1 Proteinase inhibitor SUNTORY LTD (JP) 1994-07-06 EP disclosed
US-5081284-A N-Oxomethyl-Substituted Peptide SUNTORY LIMITED (JP) 1992-01-14 US disclosed
EP-0393457-A1 Proteinase inhibitor SUNTORY LIMITED (JP) 1990-10-24 EP disclosed