Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 6/20 | 0.57 |
| ▸ | CTSS | P25774 | 5/20 | 0.57 |
| ▸ | CTSB | P07858 | 5/20 | 0.57 |
| ▸ | CTSK | P43235 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ELANE | P08246 | 3/20 | 0.49 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.46 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18359408 | 0.90 | MEN1 (0.58) | CTSLCTSSCTSBCTSKMEN1 | |
| SCHEMBL10487573 | 0.90 | MEN1 (0.58) | CTSLCTSSCTSBCTSKMEN1 | |
| SCHEMBL7334769 | 0.89 | CTSL (0.61) | CTSLCTSSCTSBCTSKMEN1 | |
| SCHEMBL9554997 | 0.88 | CTSL (0.50) | CTSLCTSSCTSBCTSKMEN1 | |
| SCHEMBL6262924 | 0.87 | CTSL (0.49) | CTSLCTSSCTSBCTSK | |
| SCHEMBL6262926 | 0.87 | CTSL (0.49) | CTSLCTSSCTSBCTSK | |
| SCHEMBL6268213 | 0.85 | NPSR1 (0.44) | MEN1KMT2ALMNAATM | |
| SCHEMBL6268212 | 0.85 | NPSR1 (0.44) | MEN1KMT2ALMNAATM | |
| SCHEMBL5205166 | 0.84 | CASP3 (0.48) | CTSLCTSSCTSBCTSKKMT2A | |
| SCHEMBL27571135 | 0.84 | CASP3 (0.48) | CTSLCTSSCTSBCTSKKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5221665-A | N-substituted amides | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1993-06-22 | — | — | US | disclosed |
| EP-0369391-A2 | N-substituted amides | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1990-05-23 | — | — | EP | disclosed |